The Institute of Metabolic Science-Metabolic Research Laboratories (IMS-MRL) and its embedded Medical Research Council (MRC) Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
IMS-MRL research groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
Latest news
Dr Eleanor Raffan announced as a 2025 Springboard awardee by the Academy of Medical Sciences
10 April 2025
Congratulations to one of our Affiliated PIs, Dr. Eleanor Raffan from the IMS-MRL and Department of Physiology, Development and Neurosciences, who has been awarded £125,000 through the Springboard programme from the Academy of Medical Sciences. This grant, alongside mentoring and career development support will allow her...
New review on the GIP receptor and metabolic control
7 April 2025
A new review article by Paula-Peace James-Okoro, PhD student with the Gribble/Reimann group, and colleagues at the IMS-MRL, which was recently published in Frontiers in Endocrinology , explores how the Glucose-dependent insulinotropic polypeptide receptor (GIPR) contributes to the regulation of appetite, body weight, and...
24 March 2025
Professor Stephen O’Rahilly was recently awarded the Berthold Medal at the 68th German Congress of Endocrinology held in Baden Baden last week. The award took place as part of the Berthold Lecture on 20th March, in which Stephen gave an insight into his scientific work with his lecture on “ Adventures in Endocrinology...
