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The Institute of Metabolic Science-Metabolic Research Laboratories (IMS-MRL) and its embedded Medical Research Council (MRC) Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
IMS-MRL research groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
Latest news
How different types of envy affect workplace ideas
30 July 2026
Envy is a natural human emotion, but it can be harmful in the workplace. Research co-authored by Jungmin Choi (Cambridge Judge Business School and IMS-MRL), published in the Journal of Creative Behaviour , finds that in evaluating colleagues’ creative ideas, people can have benign envy or malicious envy – so managers need...
21 July 2026
A research team led by Jo Lewis from the Gribble / Reimann group at the IMS-MRL have shown that the process of activating and blocking a particular gut hormone receptor takes place in two distinct areas of the brain, and can enhance weight loss when combined with weight-loss drugs like semaglutide (Wegovy). Over a billion...
A continuous molecular map of fatty liver disease points to earlier, more precise diagnosis
13 July 2026
Researchers at Cambridge, EMBL-EBI and Open Targets, together with other partners in the UK, US, Japan and Europe, show that MASLD progresses as a continuum rather than in fixed stages, and describe a blood test that pinpoints where a patient sits on that trajectory. Researchers at the Institute of Metabolic Science-...
