The Wellcome-MRC Institute of Metabolic Science-Metabolic Research Laboratories (IMS-MRL) and its embedded MRC Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease.
We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
IMS-MRL groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
The IMS-MRL is the base for the MRC Metabolic Diseases Unit which supports four programmes of research that aim to improve understanding of the mechanisms responsible for obesity and related metabolic diseases.
Together with a Welcome Strategic Award, it also supports core scientific facilities that underpin basic and experimental science at the IMS-MRL.
Latest News
Manpei Suzuki International Prize
Congratulations to Professor Stephen O’Rahilly who has won the 2019 Manpei Suzuki International Prize – a prestigious annual award made…
The Pleckstrin homology (PH) domain of SH2B1 plays a crucial role in energy homeostasis
The GOOS team have been involved in the publication of a new paper in the journal Diabetes. Previous work from…
Childhood obesity linked to structural differences in key brain regions
A study from Lisa Ronan (Psychiatry) and Paul Fletcher (Department of Psychiatry and IMS-MRL) has uncovered distinct differences in brain…
A turbulent drama happening at a cellular scale
The winning image from this year’s Reflections of Research, an annual competition run by the British Heart Foundation, was taken…
