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Institute of Metabolic Science

Metabolic Research Laboratories

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The Institute of Metabolic Science-Metabolic Research Laboratories (IMS-MRL) and its embedded Medical Research Council (MRC) Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.

IMS-MRL research groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.

Read more at: Our Research
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Our Research

Research at the Institute of Metabolic Science-Metabolic Research Laboratories is dedicated to understanding the mechanisms responsible for obesity and related metabolic diseases, with the specific aims of undertaking high quality basic science and clinical research to improve understanding of, and...


Read more at: Study with us
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Study with us

The Institute of Metabolic Science offers a world class environment for research in obesity, diabetes and cardiovascular disease. Training graduate students for a scientific career is a priority at the IMS-MRL. We have a mixture of both basic science students and clinical trainees and aim to...



Latest news

TV nutrition and health experts raise a glass to science at Cambridge’s Pint of Science festival

12 May 2026

TV nutrition and health experts will take centre stage alongside astronomers, neuroscientists and AI experts at the annual Pint of Science festival next week, with public talks in the unlikeliest of ‘lecture theatres’ – local Cambridge pubs. This year’s festival (18 th – 20 th May)_ will see twice as many events taking...

Physiological mechanisms mediating socio-environmental influences on pregnancy outcomes in Black people

29 April 2026

A University of Cambridge study led by Dr Grace Amedor and Professor Dino Giussani , an affiliated PI at the IMS-MRL and both based in the Department of Physiology, Development and Neuroscience, has found that stresses such as systemic racism and socioeconomic disadvantage may sensitise key processes in the body during...

Why do high-protein diets make you feel full? Scientists discover a molecular answer

21 April 2026

We all know that eating a high-protein meal tends to keep you fuller for longer than a high-carb or high-fat meal. But the brain mechanisms behind this have remained largely mysterious - until now. A new study published in Cell Metabolism has identified a surprising molecular player: a protein called Cav3.1, a calcium...