The University of Cambridge Metabolic Research Laboratories and its embedded MRC Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease.
We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
MRL groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
The MRL is the base for the MRC Metabolic Diseases Unit which supports four programmes of research that aim to improve understanding of the mechanisms responsible for obesity and related metabolic diseases.
Together with a Welcome Strategic Award, it also supports core scientific facilities that underpin basic and experimental science at the MRL.
Latest News
MC4R is one of the key regulators of body weight in humans. Variants in MC4R are the most commonly identified…
Steroid Receptor Coactivator (SRC)-1 modulates leptin signalling in the hypothalamus
Work led by Prof Sadaf Farooqi’s team, in collaboration with Yong Xu’s lab (Baylor College of Medicine, Houston), published today…
Dose-dependent effects of genetic PI3K activation in human pluripotent stem cells
In a paper published in PNAS, research carried out by PhD student Ralitsa Madsen and colleagues from Robert Semple’s group…
Low levels of oxygen in the womb may cause fertility issues in daughters
Researchers from the Ozanne group, working in collaboration with the Giussani lab (Dept. Physiology, Development and Neuroscience) have found that…
