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The Institute of Metabolic Science-Metabolic Research Laboratories (IMS-MRL) and its embedded Medical Research Council (MRC) Metabolic Diseases Unit investigate the mechanisms through which metabolic health is maintained and how this is disturbed in disease. We seek to use that knowledge to aid better treatment and prevention of obesity, Type 2 diabetes and related endocrine and metabolic diseases.
IMS-MRL research groups encompass skills in genetics, cell biology, cell signalling, neuroendocrinology, bioenergetics, human and animal physiology, experimental medicine and clinical trials.
Latest news
A continuous molecular map of fatty liver disease points to earlier, more precise diagnosis
13 July 2026
Researchers at Cambridge and EMBL-EBI, with partners in the UK, US, Japan and Europe, show that MASLD progresses as a continuum rather than in fixed stages, and describe a blood test that pinpoints where a patient sits on that trajectory. Researchers at the Institute of Metabolic Science-Metabolic Research Laboratories (...
Artificial pancreas technology features in NIHR Gamechangers series
7 July 2026
Technology is revolutionising the way people manage diabetes, helping patients maintain healthier blood sugar levels while reducing the burden of day-to-day care. For a long time, managing the condition meant a relentless cycle of finger-prick blood tests, precise carbohydrate counting, and manual insulin injections. Today...
Addenbrooke’s innovation expands access to advanced genome testing for cancer patients nationally
18 June 2026
A service pioneered at Addenbrooke’s Hospital that could help up to three times more cancer patients benefit from whole genome sequencing (WGS) has won a national award and been accredited for use across the UK. WGS is a cutting-edge genetic test that is available on the NHS to inform diagnosis and treatment for many...
