Wellcome-MRC Institute of Metabolic ScienceOur research in the IMS-MRL focusses on understanding metabolism and metabolic disease affecting molecules, cells, tissues, organisms and populations. This ability to successfully undertake both “bench to bedside” and “bedside to bench” approaches helps us to make new discoveries, and investigate their significance.
Our staff group has a uniquely diverse skill set, with high proficiency at a wide range of laboratory and clinical research techniques. Our IMS-MRL League of Experts provides a resource for new staff members or existing staff members to collaborate or learn new techniques.
Scroll through the table below or use the search box to look for a particular person or technique.
| Name | Areas of Expertise | |
|---|---|---|
Chris Bannon Clinical Research Associate | camb3 at medschl.cam.ac.uk | Medical education. GLP1 and gut hormones. Obesity. |
Charley Beresford Senior Animal Technician | cb625 at medschl.cam.ac.uk | Mouse metabolic phenotyping. |
Katie Duckett PhD Student/Research Assistant | kd464 at medschl.cam.ac.uk | In vitro cAMP assays. Bacterial cloning. |
Xiaowen Duan Post-doc | xd253 at medschl.cam.ac.uk | Western blotting. qRT-PCR. Insulin tolerance test in mice. Big dataset analysis. |
Denise Fernandez-Twinn Research Associate | df220 at cam.ac.uk | Project management: Animal study design and modelling; Animal licencing and compliance; Data analysis interpretation. Biochemistry: Western blotting; Immunoprecipitation; Immunohistochemistry; ELISA; Colorimetric assays. Molecular biology: Isolation and analysis of DNA and RNA from cells and tissues; Design of primers and probes; PCR; qPCR |
Sarah Grocott Chief Animal Technician (DMC) | sef34 at medschl.cam.ac.uk | Mouse phenotyping (tail bleeds etc). |
Ioannis Kamzolas Postdoctoral Research Associate | ik352 at cam.ac.uk | Bioinformatics. Big data. Omics analyses. Non-Alcoholic Fatty Liver Disease. |
Jane Kennet Research Nurse | jk605 at medschl.cam.ac.uk | Clinical research. Patient recruitment to clinical studies. |
Laura Kusinski Post doctoral Research Associate | lck34 at medschl.cam.ac.uk | Placental sampling. Clinical study coordination. Clinical study database design. |
Chris Lelliott  Head of Disease Model Core | cjl39 at medschl.cam.ac.uk | Animal licencing and compliance. Locating models/understanding data from global mouse databases. Designing animal studies. |
| Agnieszka (Agnes) Lukasik Research Assistant | al473 at medschl.cam.ac.uk | Public engagement. Events and scientific conference organisation. Staff engagement. Promoting mental health and wellbeing. |
Matteo Mastantuoni Research Animal Technician | mm2651 at medschl.cam.ac.uk | Mice handling. Embryo manipulation. Procedural work on mice. Basic laboratory techniques in biology. |
Claire Meek Principal Investigator | clm70 at cam.ac.uk | Designing and running clinical studies. Recruiting special populations. Complex intervention studies. pregnancy and childhood recruitment. |
Lucas Carminatti Pantaleao Research Associate | lp435 at medschl.cam.ac.uk | Cell biology: extensive experience culturing eukaryotic cell lines and primary cells; generation of modified cell lines with siRNA and miRNA mimics using liposome transfection; generation and screening of stable KO cell lines using CRISPR-Cas9 plasmid vectors. Cell based assays: transwell co-cultures; cell proliferation assays (e.g.: CFSE and MTT); Nile red staining of neutral lipids; Immunocytochemistry followed by fluorescent microscopy and FACS; radiolabelled fatty acid uptake and oxidation assays; SILAC. Molecular biology: Isolation and analysis of DNA and RNA from cells and tissues; design of primers and probes; PCR; qPCR; DNA recombination and molecular cloning; plasmid engineering; DNA sequence analysis; RNA-seq; sRNA-Seq; cell-based luciferase assays. Biochemistry: western blotting; immunoprecipitation; immunohistochemistry; ELISA; colorimetric assays. |
Clive Petry Senior Research Associate | cjp1002 at cam.ac.uk | Data analysis and interpretation. Editorial work. General laboratory techniques in clinical biochemistry. |
Kara Rainbow Research Assistant | kh271 at medschl.cam.ac.uk | Sanger sequencing. 10x Genomics. SNP Genotyping. |
John Tadross Academic Clinical Fellow | jt636 at cam.ac.uk | Single cell/nucleus RNA sequencing. Immunohistochemistry. In situ hybridisation. Histopathology (human and murine). |
Elizabeth Turner Clinical Research Midwife | eht27 at medschl.cam.ac.uk | Recruitment of pregnant women onto a research study. |
James Warner Chief Research Technician Histopathology Core | jw939 at medschl.cam.ac.uk | Microtomy. Cryotomy. Staining (H&E and special stains). Immunohistochemistry. In situ hybridisation (predominantly RNAscope). |
Ilona Zvetkova Core Facility Leader | Igz20 at medchl.cam.ac.uk | Various molecular biology techniques. Design, planning, delivery and troubleshooting of CRISPR editing projects (mainly generation of in vivo CRISPR mouse models). Mouse model phenotyping. Genomics (including epigenetics). |
