skip to content

Institute of Metabolic Science

Metabolic Research Laboratories
 
Read more at: Liver fat – always the enemy?
photo of a scientific graph

Liver fat – always the enemy?

25 September 2024

A study led by Sam Lockhart, Milan Muso , Steve O’Rahilly and others at the IMS-MRL, working with collaborators at the Universities of California, Newcastle and Leicester, has discovered that having some fat (specifically, a type of fat known as triglyceride) in liver cells may help the liver from being seriously damaged...


Read more at: MicroRNA-483: a missing link between the major growth factors IGF2 and IGF1
Picture to support research paper

MicroRNA-483: a missing link between the major growth factors IGF2 and IGF1

23 September 2024

Researchers from the Constancia group led by Ionel Sandovici and Denise Fernandez-Twinn, the Ozanne group and many other colleagues at the IMS-MRL, working in collaboration with the Universities of Cambridge, Glasgow, Montreal and Vienna, have unravelled a previously unrecognized link between Insulin-like growth factor 1 (...


Read more at: University of Cambridge, UCL and King’s researchers awarded UKRI funding for type 2 diabetes research

University of Cambridge, UCL and King’s researchers awarded UKRI funding for type 2 diabetes research

13 September 2024

Dr Daniel Fazakerley from the IMS-MRL, Dr Ivo Lieberam (King’s College London) and Professor Wenhui Song (University College London) are collaborating on a diabetes research project that has been awarded a total of £1.2m in funding from the UK Research and Innovation (UKRI)’s new interdisciplinary scheme. The project will...


Read more at: Cambridge-led study discovers cause of pregnancy sickness – and potential treatment
photo of a pregnant belly

Cambridge-led study discovers cause of pregnancy sickness – and potential treatment

13 December 2023

A collaborative study led by Professor Sir Stephen O’Rahilly , has shown why many women experience nausea and vomiting during pregnancy – and why some women, including the Duchess of Cambridge, become so sick they need to be admitted to hospital. The culprit is a hormone produced by the fetus – a protein known as GDF15...


Read more at: New study suggests need for more research into the use of metformin in pregnancy
graphical abstract for this paper

New study suggests need for more research into the use of metformin in pregnancy

17 November 2022

Metformin is used to treat gestational diabetes mellitus in several countries including the UK. Although the medication is beneficial for the mother and safe for her baby, we do not know if there are any long-term effects for her children. In a recent study, published in Diabetologia , researchers at the IMS-MRL led by PhD...