In a new study published in The New England Journal of Medicine, a team led by Professor Sadaf Farooqi, found that 1 in 100 children with severe obesity from the GOOS cohort, have mutations in GNAS which encodes Gαs (stimulatory G-protein alpha subunit). GNAS mutations typically cause a condition called pseudohypoparathyroidism (PHP) and impair signalling […]
Making new fat to control inflammation
In a recent study funded by the British Heart Foundation, Guillaume Bidault and members of the TVP group, working with colleagues from the MRC LMB, provide some important new insights into how making fat in immune cells might help to fight disease. Immune cell activation defends the body against foreign agents such as bacteria, viruses, […]
Stephen O’Rahilly and Sadaf Farooqi jointly awarded the 2022 Croonian Medal of The Royal Society
Congratulations to Professors Stephen O’Rahilly and Sadaf Farooqi who are announced today as winners of the Royal Society’s prestigious Croonian Medal “for their seminal discoveries regarding the control of human body weight, resulting in novel diagnostics and therapies, which improve human health”. The Croonian Medal has been awarded annually since 1728 and its recipients […]
First trial of artificial pancreas for outpatients living with type 2 diabetes
The artificial pancreas developed at the Institute of Metabolic Science and Cambridge University Hospitals NHS Foundation Trust has so far been available only to people living with type 1 diabetes. In research published today in Nature Medicine, the Cambridge team – working with researchers at Bern University Hospital and the University of Bern, Switzerland – […]
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