The aim of the core is to provide high quality imaging capability for researchers at the Metabolic Research Labs.
To enable the localisation and monitoring of cellular and subcellular events we provide a number of microscopes within the MRL that allow fixed- and live-preparation investigations. These currently include:
- Simple epifluorescense microscopes within tissue-culture facilities
- Widefield epi-flourescence and colour brightfield inverted microscopes
- Fully incubated laser scanning confocal microscopes (Zeiss 510 Meta and Leica SP8)
- Zeiss Axioscan Z1 slide scanning microscope (Brightfield and Fluorescent)
In addition, higher resolution [super-resolution structured illumination (SSIM) and localisation microscopy (e.g. PALM and STORM)] and specialist techniques such as total internal reflection fluorescence microscopy (TIRF) are available through affiliation with the Core Microscope Facilities at the Cambridge Institute for Medical Research (CIMR).
For off-line analysis we provide additional workstations with specialist software (e.g. Halo, Imaris and Volocity) at the MRL.
For all enquiries regarding use of and initial training on MRL microscopes or to arrange bookings of the CIMR microscopes, please contact Gregory Strachan (firstname.lastname@example.org).