The MRC Metabolic Disease Unit has created three New Blood Fellowships to support outstanding candidates at the start of their independent academic careers. These prestigious fellowships are intended for basic scientists working in the broad area of metabolic disease who have already demonstrated exceptional talent and the clear potential to become an international leader in their field.
The current fellows under this programme are:
Click on a New Blood Fellow photo to view their profile page.
Clemence’s lab is focused on the characterization of the mechanisms implicated in brain amino acid detection in the regulation of energy balance. This research will improve our understanding of the pathways implicated in the regulation of body weight and potentially identify novel therapeutic targets for the treatment of obesity.
Florian T. Merkle
As a New Blood MRC fellow, Florian will study how much neuropeptide Y (NPY) and agouti-related peptide (AgRP) neurons release in response to external signals. These so-called NPY/AgRP neurones so potently stimulate feeding that if they are experimentally killed off in adult mice, the mice completely stop eating.
In this project Kevin will analyze the regulation of clathrin-dependent endocytosis by GPCRs, an approach that has never been taken previously, and analyze the consequences of this regulation and whether it is dysregulated in metabolic diseases.