A study published today in Cell Reports suggests that a large mixed-meal tolerance test may detect individuals with metabolic disease earlier than existing tests and allow better targeting of lifestyle and pharmacological interventions. As growing obesity levels begin to drive epidemics of metabolic disease, including type II diabetes and cardiovascular disease, the question of how […]
On Feb 1st Prof Sir Steve O’Rahilly reprised his 2016 Harveian Oration, originally given to Fellows of the Royal College of Physicians, for the Department of Medicine Grand Round series.
A large-scale genetic study has provided strong evidence that the development of insulin resistance – a risk factor for type 2 diabetes and heart attacks and one of the key adverse consequences of obesity – results from the failure to safely store excess fat in the body. Overeating and lack of physical activity worldwide has […]